Characterization of a Novel Rat Epididymal Cell Line to Study Epididymal Function
نویسندگان
چکیده
منابع مشابه
Characterization of epididymal proteins Electrophoretic analysis of epididymal fluid proteins
© 1998 Journals of Reproduction and Fertility 1359-6004/98 $12.50 Before mammalian spermatozoa can interact with the egg in vivo, they are subjected to post-testicular modifications in the male as well as in the female genital tract. The evidence that this post-testicular maturation process requires exposure to a specific microenvironment within the epididymis has been reviewed elsewhere (Orgeb...
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Estrogen is synthesized in the male reproductive system and is found in high concentrations in rete testis and seminal fluids. This luminal estrogen targets estrogen receptors (ER) along the male reproductive tract, and in particular the efferent ductules, where ERalpha is abundant. However, both ERalpha and ERbeta are found in various regions of the male reproductive tract. The transgenic ER k...
متن کاملCharacterization of nucleoside transport systems in cultured rat epididymal epithelium.
The nucleoside transport systems in cultured epididymal epithelium were characterized and found to be similar between the proximal (caput and corpus) and distal (cauda) regions of the epididymis. Functional studies revealed that 70% of the total nucleoside uptake was Na(+) dependent, while 30% was Na(+) independent. The Na(+)-independent nucleoside transport was mediated by both the equilibrati...
متن کاملFunctional studies of acid transporter in cultured rat epididymal cell.
OBJECTIVE To explore the functional role of vacuolar H(+)-ATPase in the pH regulation of epididymal fluid and its effect on sperm motility. DESIGN Experimental study. SETTING Physiology laboratory in a university. ANIMAL(S) Immature male Sprague-Dawley rats. INTERVENTION(S) The H(+)-ATPase inhibitor was applied to the primary culture of epididymal cells. MAIN OUTCOME MEASURE(S) The in...
متن کاملLCN6, a novel human epididymal lipocalin
BACKGROUND The lipocalin (LCN) family of structurally conserved hydrophobic ligand binding proteins is represented in all major taxonomic groups from prokaryotes to primates. The importance of lipocalins in reproduction and the similarity to known epididymal lipocalins prompted us to characterize the novel human epididymal LCN6. METHODS AND RESULTS LCN6 cDNA was identified by database analysi...
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ژورنال
عنوان ژورنال: Endocrinology
سال: 2005
ISSN: 0013-7227,1945-7170
DOI: 10.1210/en.2004-1634